diff --git a/NativeScript/ffi/jni/jsi/jni/LRUCache.h b/NativeScript/ffi/jni/jsi/jni/LRUCache.h
index 7b829c3dd..afceeb132 100644
--- a/NativeScript/ffi/jni/jsi/jni/LRUCache.h
+++ b/NativeScript/ffi/jni/jsi/jni/LRUCache.h
@@ -100,6 +100,16 @@ class LRUCache {
             }
         }
 
+        void clear() {
+            if (m_evictCallback != nullptr) {
+                for (auto& entry : m_key_to_value) {
+                    m_evictCallback(entry.second.first, m_state);
+                }
+            }
+            m_key_to_value.clear();
+            m_key_tracker.clear();
+        }
+
         void update(const key_type& key, const value_type& value) {
             jweak ref = m_loadCallback(key, m_state);
             insert(key, ref);
diff --git a/NativeScript/ffi/jni/jsi/metadata/MetadataNode.cpp b/NativeScript/ffi/jni/jsi/metadata/MetadataNode.cpp
index 6187a585d..18c937afe 100644
--- a/NativeScript/ffi/jni/jsi/metadata/MetadataNode.cpp
+++ b/NativeScript/ffi/jni/jsi/metadata/MetadataNode.cpp
@@ -1307,6 +1307,12 @@ std::vector<MetadataNode::MethodCallbackData *> MetadataNode::SetClassMembersFro
         callbackData->candidates.push_back(std::move(entry));
         callbackData->objectManager = objectManager;
     }
+    for (const auto &extension: collectedExtensionMethods) {
+        if (std::find(instanceMethodData.begin(), instanceMethodData.end(), extension.second) ==
+            instanceMethodData.end()) {
+            cache->methodCallbackData.push_back(extension.second);
+        }
+    }
     auto instanceFieldCount = *reinterpret_cast<uint16_t *>(curPtr);
     curPtr += sizeof(uint16_t);
     for (auto i = 0; i < instanceFieldCount; i++) {
@@ -1392,6 +1398,7 @@ std::vector<MetadataNode::MethodCallbackData *> MetadataNode::SetClassMembersFro
         auto &methodName = entry.getName();
         if (methodName != lastMethodName) {
             callbackData = new MethodCallbackData(this);
+            cache->methodCallbackData.push_back(callbackData);
             auto method = JsFunction::createFromHostFunction(
                     rt, engine::PropNameID::forAscii(rt, methodName), 0,
                     [callbackData](JsRuntime &rt, const JsValue &thisVal, const JsValue *args,
@@ -2556,6 +2563,7 @@ void MetadataNode::SetMissingBaseMethods(
 
             if (callbackData == nullptr) {
                 callbackData = new MethodCallbackData(this);
+                GetMetadataNodeCache(rt)->methodCallbackData.push_back(callbackData);
                 auto proto = constructor.getPropertyAsObject(rt, "prototype");
                 auto method = JsFunction::createFromHostFunction(
                         rt, engine::PropNameID::forAscii(rt, methodName), 0,
@@ -2613,6 +2621,9 @@ void MetadataNode::onDisposeRuntime(JsRuntime &rt) {
             for (const auto &entry: it->extendedClassCallbackData) {
                 delete entry;
             }
+            for (const auto &entry: it->methodCallbackData) {
+                delete entry;
+            }
         }
         s_metadata_node_cache.Remove(key);
         delete it;
diff --git a/NativeScript/ffi/jni/jsi/metadata/MetadataNode.h b/NativeScript/ffi/jni/jsi/metadata/MetadataNode.h
index 2c06df48a..265783b4a 100644
--- a/NativeScript/ffi/jni/jsi/metadata/MetadataNode.h
+++ b/NativeScript/ffi/jni/jsi/metadata/MetadataNode.h
@@ -373,6 +373,9 @@ class MetadataNode {
         std::vector<FieldCallbackData *> fieldCallbackData;
         std::vector<PropertyCallbackData *> propertyCallbackData;
         std::vector<ExtendedClassCallbackData *> extendedClassCallbackData;
+        // Method callback data no CtorFuncCache entry owns: static methods,
+        // extension-only methods and methods copied from a skipped base class.
+        std::vector<MethodCallbackData *> methodCallbackData;
     };
 
     static bool s_profilerEnabled;
diff --git a/NativeScript/ffi/jni/jsi/objectmanager/ObjectManager.cpp b/NativeScript/ffi/jni/jsi/objectmanager/ObjectManager.cpp
index 394a45446..08e000964 100644
--- a/NativeScript/ffi/jni/jsi/objectmanager/ObjectManager.cpp
+++ b/NativeScript/ffi/jni/jsi/objectmanager/ObjectManager.cpp
@@ -85,6 +85,10 @@ void ObjectManager::OnDisposeRuntime() {
     m_idToObject.clear();
     m_jsObjectCtor = JsFunction();
 
+    // Its destructor leaves the weak global refs alive, and the process-wide
+    // weak reference table is finite.
+    m_cache.clear();
+
     // The host-object proxies are owned by the *engine*, and each holds an owned
     // handle to the instance it wraps. Nothing above reaches them: they are only
     // destroyed when the engine tears its heap down, at which point
diff --git a/NativeScript/ffi/jni/napi/jni/LRUCache.h b/NativeScript/ffi/jni/napi/jni/LRUCache.h
index 7b829c3dd..afceeb132 100644
--- a/NativeScript/ffi/jni/napi/jni/LRUCache.h
+++ b/NativeScript/ffi/jni/napi/jni/LRUCache.h
@@ -100,6 +100,16 @@ class LRUCache {
             }
         }
 
+        void clear() {
+            if (m_evictCallback != nullptr) {
+                for (auto& entry : m_key_to_value) {
+                    m_evictCallback(entry.second.first, m_state);
+                }
+            }
+            m_key_to_value.clear();
+            m_key_tracker.clear();
+        }
+
         void update(const key_type& key, const value_type& value) {
             jweak ref = m_loadCallback(key, m_state);
             insert(key, ref);
diff --git a/NativeScript/ffi/jni/napi/metadata/MetadataNode.cpp b/NativeScript/ffi/jni/napi/metadata/MetadataNode.cpp
index 6e9e48219..582386eb5 100644
--- a/NativeScript/ffi/jni/napi/metadata/MetadataNode.cpp
+++ b/NativeScript/ffi/jni/napi/metadata/MetadataNode.cpp
@@ -1584,6 +1584,12 @@ std::vector<MetadataNode::MethodCallbackData *> MetadataNode::SetClassMembersFro
         callbackData->candidates.push_back(std::move(entry));
         callbackData->objectManager = objectManager;
     }
+    for (const auto &extension: collectedExtensionMethods) {
+        if (std::find(instanceMethodData.begin(), instanceMethodData.end(), extension.second) ==
+            instanceMethodData.end()) {
+            GetMetadataNodeCache(env)->methodCallbackData.push_back(extension.second);
+        }
+    }
     auto instanceFieldCount = *reinterpret_cast<uint16_t *>(curPtr);
     curPtr += sizeof(uint16_t);
     for (auto i = 0; i < instanceFieldCount; i++) {
@@ -1657,6 +1663,7 @@ std::vector<MetadataNode::MethodCallbackData *> MetadataNode::SetClassMembersFro
         auto &methodName = entry.getName();
         if (methodName != lastMethodName) {
             callbackData = new MethodCallbackData(this);
+            GetMetadataNodeCache(env)->methodCallbackData.push_back(callbackData);
             napi_value method;
             NAPI_GUARD(napi_create_function(env, methodName.c_str(), methodName.size(), MethodCallback,
                                  callbackData, &method)) {}
@@ -3054,6 +3061,7 @@ void MetadataNode::SetMissingBaseMethods(
 
             if (callbackData == nullptr) {
                 callbackData = new MethodCallbackData(this);
+                GetMetadataNodeCache(env)->methodCallbackData.push_back(callbackData);
                 napi_value proto = napi_util::get_prototype(env, constructor);
                 napi_value method;
                 NAPI_GUARD(napi_create_function(env, methodName.c_str(), NAPI_AUTO_LENGTH, MethodCallback,
@@ -3105,6 +3113,9 @@ void MetadataNode::onDisposeEnv(napi_env env) {
             for (const auto &entry: it->fieldCallbackData) {
                 delete entry;
             }
+            for (const auto &entry: it->methodCallbackData) {
+                delete entry;
+            }
         }
         s_metadata_node_cache.Remove(env);
         delete it;
diff --git a/NativeScript/ffi/jni/napi/metadata/MetadataNode.h b/NativeScript/ffi/jni/napi/metadata/MetadataNode.h
index b6c699436..fabe0f507 100644
--- a/NativeScript/ffi/jni/napi/metadata/MetadataNode.h
+++ b/NativeScript/ffi/jni/napi/metadata/MetadataNode.h
@@ -360,6 +360,9 @@ class MetadataNode {
         robin_hood::unordered_map<MetadataTreeNode *, CtorCacheData> CtorFuncCache;
         robin_hood::unordered_map<std::string, MetadataNode::ExtendedClassCacheData> ExtendedCtorFuncCache;
         std::vector<FieldCallbackData *> fieldCallbackData;
+        // Method callback data no CtorFuncCache entry owns: static methods,
+        // extension-only methods and methods copied from a skipped base class.
+        std::vector<MethodCallbackData *> methodCallbackData;
     };
 
     static bool s_profilerEnabled;
diff --git a/NativeScript/ffi/jni/napi/objectmanager/ObjectManager.cpp b/NativeScript/ffi/jni/napi/objectmanager/ObjectManager.cpp
index a5c67014a..7bafbfe41 100644
--- a/NativeScript/ffi/jni/napi/objectmanager/ObjectManager.cpp
+++ b/NativeScript/ffi/jni/napi/objectmanager/ObjectManager.cpp
@@ -92,6 +92,10 @@ void ObjectManager::OnDisposeEnv() {
         NAPI_GUARD(napi_delete_reference(m_env, entry.second)) {}
     }
     m_idToObject.clear();
+
+    // Its destructor leaves the weak global refs alive, and the process-wide
+    // weak reference table is finite.
+    m_cache.clear();
 }
 
 napi_value ObjectManager::GetOrCreateProxyWeak(jint javaObjectID, napi_value instance) {
diff --git a/NativeScript/runtime/android/jsi/Runtime.cpp b/NativeScript/runtime/android/jsi/Runtime.cpp
index 7991157d2..8290b1406 100644
--- a/NativeScript/runtime/android/jsi/Runtime.cpp
+++ b/NativeScript/runtime/android/jsi/Runtime.cpp
@@ -547,6 +547,8 @@ Runtime::~Runtime() {
             close(m_mainLooper_fd[1]);
         }
     }
+
+    JEnv().DeleteGlobalRef(m_runtime);
 }
 
 std::string Runtime::ReadFileText(const std::string &filePath) {
diff --git a/NativeScript/runtime/android/napi/Runtime.cpp b/NativeScript/runtime/android/napi/Runtime.cpp
index 49fc0455f..c6f0ce75e 100644
--- a/NativeScript/runtime/android/napi/Runtime.cpp
+++ b/NativeScript/runtime/android/napi/Runtime.cpp
@@ -486,6 +486,8 @@ Runtime::~Runtime() {
             close(m_mainLooper_fd[1]);
         }
     }
+
+    JEnv().DeleteGlobalRef(m_runtime);
 }
 
 std::string Runtime::ReadFileText(const std::string &filePath) {