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ChenHsieh/README.md

Chen (Benjamin) Hsieh Β· 謝晨

Bioinformatics PhD candidate at the University of Georgia, defending in Fall/Winter 2026. My dissertation is on gene duplication in Populus, but lately most of my attention has gone to genomic foundation models β€” specifically, how robust and interpretable they actually are.

The question I keep pulling on: these models post strong benchmark numbers, but biologically meaningless edits will still flip their predictions. I attack them under constraints a biologist would accept, then look inside to see what actually changed.

I'm looking for computational biology / ML research roles starting Fall 2026 β€” especially work on evaluating and interpreting models over biological sequence data β€” and I also do management consulting. Five peer-reviewed papers so far, mostly plant genomics.

Now

  • Probing the robustness & interpretability of genomic foundation models
  • Consulting part-time with the Computational Biology Consulting Group at UGA's Institute of Bioinformatics
  • Building portable, agent-driven research tooling

Selected work

agentic-research-toolkit Portable agentic research workflows (SKILL.md) written for discovery over confirmation
biosafe-genai-network Mapping the who's-who in biosafety + AI
HATCH2024-nutrigenomics A plant-based diet planner for space missions β€” Snakemake + OpenAI API + Streamlit (HATCH 2024)
bioLOLPython Analyze biological sequences with internet slang β€” live demo
IOB_seminar_transcript Whisper-transcribed archive of the UGA Institute of Bioinformatics seminar series

More, including a 14-day RNA-seq tutorial series, on my site.

Elsewhere

Pinned Loading

  1. biosafe-genai-network biosafe-genai-network Public

    mapping the who's who in biosafety+AI

    HTML

  2. slurm-receipt slurm-receipt Public

    see what your HPC compute really cost

    Python

  3. dna2oiia dna2oiia Public

    A Python package that converts DNA sequences into sound using oiia phonetics

    Python 1

  4. sapelo2-boilerplate sapelo2-boilerplate Public

    how I use the sapelo2

    Batchfile

  5. MMP_screening MMP_screening Public

    Empowering mentors to review and engage with mentees for the Project TYRA MMP

    Python 6 2

  6. TsailabBioinformatics/AGEseq2 TsailabBioinformatics/AGEseq2 Public

    Analysis of Genome Editing by Sequencing

    Python 1